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Search Results for " antibacterial agent "

252

抑制剂 & 化合物

22

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T9612	Antibacterial agent 27	Anti-infection	Microbiology/Virology
	Antibacterial agent 27 是抗菌化合物，显示出有效的抗念珠菌活性。
T72047	Antibacterial agent 125	Antibacterial	Microbiology/Virology
	Antibacterial agent 125 是一种抗菌剂。Antibacterial agent 125 对临床相关的革兰氏阳性病原体具有有效的抗菌活性，MIC50值范围为 0.25 - 8 μM。Antibacterial agent 125 可用于抗菌药物耐药性研究。
T38886	Antibacterial agent 61
	Antibacterial agent 61 (example 27) is a antibacterial agent.
T38874	Antibacterial agent 35
	Antibacterial Agent 35 (AA35) is a potent antibacterial agent that effectively reduces the minimum inhibitory concentration (MIC) of Ceftazidime, another antibacterial agent.
T38866	Antibacterial agent 39
	Antibacterial agent 39 is a potent compound that exhibits antibacterial properties. It effectively reduces the minimum inhibitory concentration (MIC) of Ceftazidime, another antibacterial agent.
T38939	Antibacterial agent 38
	Antibacterial agent 38 is an effective antibacterial agent. It can be utilized in the scientific investigation of bacterial infections.
T40301	Antibacterial agent 28
	Antibacterial agent 28, with a minimum inhibitory concentration (MIC) range of 0.5-2 μg/mL, exhibits promising potential as an antibacterial candidate targeting MRSA infections.
T38916	Antibacterial agent 51
	Antibacterial agent 51 (example 45) is a potent antibacterial compound effective against E. coli strains NCTC 13351, M 50, and 7 MP, with MIC values of 4, 8, and 8 mcg/mL, respectively (WO2013030733A1).
T38877	Antibacterial agent 52
	Antibacterial agent 52 (example 18) is a antibacterial agent.
T40338	Antibacterial agent 31
	Antibacterial agent 31 exhibits (shows) efficacy (activity) in combating (against) rice bacterial leaf streak.
T39249	Antibacterial agent 40
	Antibacterial agent 40 is an antibacterial agent.
T38881	Antibacterial agent 56
	Antibacterial agent 56 (example 22) is a antibacterial agent.
T38879	Antibacterial agent 54
	Antibacterial agent 54 (example 20) is a antibacterial agent.
T38865	Antibacterial agent 41
	Antibacterial agent 41 (example 3) is a antibacterial agent.
T38870	Antibacterial agent 45
	Antibacterial Agent 45 (AA45) exemplifies a potent antibacterial compound that effectively reduces the minimal inhibitory concentration (MIC) value of Ceftazidime, another antibacterial agent.
T38917	Antibacterial agent 50
	Antibacterial agent 50 (example 47) is a compound that exhibits antibacterial activity. It shows minimum inhibitory concentration (MIC) values of 32, 64, and 128 mcg/mL against three strains of E. coli, namely NCTC 13351, M 50, and 7 MP, respectively (WO2013030733A1).
T38884	Antibacterial agent 57
	Antibacterial agent 57 (example 25) is a antibacterial agent.
T38880	Antibacterial agent 55
	Antibacterial agent 55 (example 21) is a antibacterial agent.
T38876	Antibacterial agent 33
	Antibacterial Agent 33, a potent antibacterial compound, effectively decreases the minimum inhibitory concentration (MIC) of Ceftazidime, another antibacterial agent.
T38867	Antibacterial agent 42
	Antibacterial Agent 42 demonstrates potent antibacterial activity by effectively reducing the Minimum Inhibitory Concentration (MIC) of the broad-spectrum antibacterial agent Ceftazidime.
T38871	Antibacterial agent 46
	Antibacterial agent 46, serves as a potent antibacterial compound. With its versatile properties, this agent demonstrates considerable potential for supporting research on bacterial infections.
T38938	Antibacterial agent 37
	Antibacterial agent 37 is an effective antimicrobial compound. It holds potential as a valuable tool for researching bacterial infections.
T40316	Antibacterial agent 30
	Antibacterial agent 30 exhibits remarkable in vitro activity against Xoo, as evidenced by its EC50 value of 1.9 μg/mL.
T38915	Antibacterial agent 32
	Antibacterial agent 32 exhibits potent antimicrobial activity against E. coli strains NCTC 13351, M 50, and 7 MP, with minimum inhibitory concentration (MIC) values of 1 mcg/mL, 2 mcg/mL, and 8 mcg/mL, respectively (WO2013030733A1, example 43).
T38883	Antibacterial agent 59
	Antibacterial agent 59 (example 24) is a antibacterial agent.
T38878	Antibacterial agent 53
	Antibacterial agent 53 (example 19) is a antibacterial agent.
T38873	Antibacterial agent 49
	Antibacterial agent 49 (example 12) is a antibacterial agent.
T38882	Antibacterial agent 58
	Antibacterial Agent 58 (AA58) is a potent antibacterial compound that effectively reduces the minimum inhibitory concentration (MIC) value of Ceftazidime, another antibacterial agent.
T38885	Antibacterial agent 60
	Antibacterial agent 60 is a potent compound that effectively reduces the minimum inhibitory concentration (MIC) of Ceftazidime, an antibacterial agent.
T38872	Antibacterial agent 47
	Antibacterial Agent 47 demonstrates potent antibacterial activity as an adjunct therapy to parenteral antibiotic Ceftazidime. By effectively reducing the minimum inhibitory concentration (MIC) of Ceftazidime, Antibacterial Agent 47 acts as a highly promising antimicrobial agent, thereby enhancing the overall efficacy of the treatment.
T38875	Antibacterial agent 34
	Antibacterial agent 35 is a compound that effectively reduces the minimum inhibitory concentration (MIC) of Ceftazidime, enhancing its antibacterial activity.
T38868	Antibacterial agent 43
	Antibacterial agent 43, is a potent antibacterial compound. It exhibits promising activity against bacterial infections and offers great potential for research purposes.
T38869	Antibacterial agent 44
	Antibacterial agent 44 is a novel antibacterial compound (WO2013030735A1, example 7). It exhibits potent antibacterial activity and is suitable for research purposes related to the study of bacterial infections.
T36657	Antibacterial agent 18
	Antibacterial agent 18, a multi-arm AIE molecule, demonstrates efficacy against both Gram-positive and Gram-negative bacteria. Antibacterial agent 18 functions by conjugating with the cell wall of bacteria with rigid arm configuration, thereby interfering with the sugar and peptide processes essential for cell wall turning. This mechanism inhibits or eradicates bacterial growth[1].
T9680	Irloxacin	Antibacterial	Microbiology/Virology
	Irloxacin 是一种口服活性的喹诺酮类抗菌剂，在酸性条件下具有更强大的活性。在体外，Irloxacin 对革兰氏阳性菌和革兰氏阴性菌都具有良好的抗菌谱。
T61159	Antibacterial agent 26	Antibacterial	Microbiology/Virology
	Antibacterial agent 26 是一种抗菌化合物，是有效的DHFR 抑制剂（金黄色葡萄球菌DHFR Ki 为0.020 nM）。
T72309	Antibacterial agent 131	Antibacterial	Microbiology/Virology
	Antibacterial agent 131 是一种具有抗菌作用的化合物。
T72310	Antibacterial agent 132	Antifungal	Microbiology/Virology
	Antibacterial agent 132 对 C. parapsilosis (ATCC 22019) 和 C. krusei (ATCC 6258) 实验中显示出抗菌作用，MIC90 值分别为 <0.06 μg/mL 和 62.50 μg/mL。Antibacterial agent 132 对芳香化酶 (aromatase enzyme)具有抑制作用，IC50 为 0.047μM。
T0274	Cinoxacin 西诺沙星,Compound 64716	Topoisomerase; Antibacterial; Antibiotic	DNA Damage/DNA Repair; Microbiology/Virology
	Cinoxacin (Compound 64716) 是一种喹诺酮类的合成抗生素, 与Oxolinic acid 和 Nalidixic acid 活性相似。
T21435	Sulfamoxole 磺胺二甲唑,NSC 683535,Oxasulfa,Sulfamoxol,NSC683535,Oxazole,NSC-683535	Antibacterial	Microbiology/Virology
	Sulfamoxole (Sulfamoxol) 是一种广谱化疗抗菌剂，可用于小儿感染的相关研究。
T62120	Antibacterial agent 79
	Antibacterial agent 79 是一种抗菌剂。
T62880	Antibacterial agent 99
	Antibacterial agent 99 (compound 7b) 是一种有效的抗菌剂。Antibacterial agent 99 具有显著的抗菌和抗真菌作用，且没有溶血活性。
T63224	Antibacterial agent 104
	Antibacterial agent 104 是有效的抗细菌 (antibacterial) 剂，体外具有显著的抗细菌作用，体内表现出良好的抗 MRSA 效果。
T60455	Antibacterial agent 65
	Antibacterial agent 65 是潜在的抗菌剂和抗氧化剂。
T63252	Antibacterial agent 113
	Antibacterial agent 113 是有效的抗菌剂 (antibacterial)，对P.aeruginosa、S.mutans、B.subtilis、E.coli、E.faecalis、S.typhimuriumand 和S.aureus microorganisms 表现出抗菌作用，MIC 值均为 15625 μM。
T61170	Antibacterial agent 96
	Antibacterial agent 96 (compound 4k) 是一种有效的抗菌剂。Antibacterial agent 96 对药物敏感和耐多药的结核分枝杆菌 (M.tuberculosis)显示出抗结核活性。Antibacterial agent 96 对 HepG2 和 Vero 细胞有毒性。
T61123	Antibacterial agent 111
	Antibacterial agent 111 (Compound 3) exhibits potent antibacterial activity against B. cereus and K. pneumonia, with MIC values of 3.90 μg/mL and 0.49 μg/mL, respectively. It achieves this antibacterial effect by strongly binding to specific residues of tyrosyl-tRNA synthetase [1].
T73911	Antibacterial agent 12
	Antibacterial agent 12 是一种联芳基恶唑烷酮类似物，是一种针对抗生素敏感和耐药革兰氏阳性菌的抗菌剂。
T62627	Antibacterial agent 69
	Antibacterial agent 69 是一种新型结构抗菌调节剂，并被用来对抗致命的耐多药细菌感染 (MICs: 2.978 μM)。
T72303	Antibacterial agent 124
	Antibacterial agent 124 是一种有效的细菌脯氨酸-tRNA 合成酶 (ProRS) 抑制剂，对 Staphylococcus aureusProRS (SaProRS) 的 IC50为 0.18 μM。

化合物

Antibacterial agent 27

Cat.No: T9612

Target: Anti-infection

Antibacterial agent 125

Cat.No: T72047

Target: Antibacterial

Antibacterial agent 61

Cat.No: T38886

Antibacterial agent 35

Cat.No: T38874

Antibacterial agent 39

Cat.No: T38866

Antibacterial agent 38

Cat.No: T38939

Antibacterial agent 28

Cat.No: T40301

Antibacterial agent 51

Cat.No: T38916

Antibacterial agent 52

Cat.No: T38877

Antibacterial agent 31

Cat.No: T40338

Antibacterial agent 40

Cat.No: T39249

Antibacterial agent 56

Cat.No: T38881

Antibacterial agent 54

Cat.No: T38879

Antibacterial agent 41

Cat.No: T38865

Antibacterial agent 45

Cat.No: T38870

Antibacterial agent 50

Cat.No: T38917

Antibacterial agent 57

Cat.No: T38884

Antibacterial agent 55

Cat.No: T38880

Antibacterial agent 33

Cat.No: T38876

Antibacterial agent 42

Cat.No: T38867

Antibacterial agent 46

Cat.No: T38871

Antibacterial agent 37

Cat.No: T38938

Antibacterial agent 30

Cat.No: T40316

Antibacterial agent 32

Cat.No: T38915

Antibacterial agent 59

Cat.No: T38883

Antibacterial agent 53

Cat.No: T38878

Antibacterial agent 49

Cat.No: T38873

Antibacterial agent 58

Cat.No: T38882

Antibacterial agent 60

Cat.No: T38885

Antibacterial agent 47

Cat.No: T38872

Antibacterial agent 34

Cat.No: T38875

Antibacterial agent 43

Cat.No: T38868

Antibacterial agent 44

Cat.No: T38869

Antibacterial agent 18

Cat.No: T36657

Cat.No: T9680

Target: Antibacterial

Antibacterial agent 26

Cat.No: T61159

Target: Antibacterial

Antibacterial agent 131

Cat.No: T72309

Target: Antibacterial

Antibacterial agent 132

Cat.No: T72310

Target: Antifungal

Cat.No: T0274

Synonym: 西诺沙星,Compound 64716

Target: Topoisomerase, Antibacterial, Antibiotic

Cat.No: T21435

Synonym: 磺胺二甲唑,NSC 683535,Oxasulfa,Sulfamoxol,NSC683535,Oxazole,NSC-683535

Target: Antibacterial

Antibacterial agent 79

Cat.No: T62120

Antibacterial agent 99

Cat.No: T62880

Antibacterial agent 104

Cat.No: T63224

Antibacterial agent 65

Cat.No: T60455

Antibacterial agent 113

Cat.No: T63252

Antibacterial agent 96

Cat.No: T61170

Antibacterial agent 111

Cat.No: T61123

Antibacterial agent 12

Cat.No: T73911

Antibacterial agent 69

Cat.No: T62627

Antibacterial agent 124

Cat.No: T72303

Cat. No.	Product Name	Target	Signaling Pathways
T20446	Creosol	Endogenous Metabolite	Metabolism
	Creosol 是内源性代谢产物的一种。
T13355	Xanthorrhizol	Antibacterial	Microbiology/Virology
	Xanthorrhizol 是从 Curcuma xanthorrhiza 中分离的一种抗菌剂。
T1314	Triclosan Irgasan,三氯生,Cloxifenolum	NADPH; Antibacterial; Antibiotic; Autophagy; Antifungal	Autophagy; Metabolism; Microbiology/Virology
	Triclosan (Irgasan) 是一种在消费类产品中发现的抗菌剂和抗真菌剂，如肥皂, 洗涤剂, 玩具, 和手术清洗用品。
T3018	Protocatechualdehyde Protocatechuic aldehyde,3,4-Dihydroxybenzaldehyde,Rancinamycin IV,Catechaldehyde,原儿茶醛	Reactive Oxygen Species; Antibacterial	Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB
	Protocatechualdehyde (3,4-Dihydroxybenzaldehyde), a natural polyphenol compound derived from radix Salviae Miltiorrhizae roots, exhibits diverse biological activities and finds extensive medicinal applications as an antioxidant, anti-aging, antibacterial, and anti-inflammatory agent.
TN6746	(-)-TERPINEN-4-OL	Antibacterial	Microbiology/Virology
	(-)-TERPINEN-4-OL 可用作抗金黄色葡萄球菌的抗菌剂和抗生物膜剂。
T8046	Tosufloxacin tosylate hydrate Tosufloxacin p-Toluenesulfonate Hydrate,A-61827 tosylate hydrate,对甲苯磺酸妥舒沙星水合物,T-3262 Tosylate Hydrate	Others; Antibacterial; Antibiotic	Microbiology/Virology; Others
	Tosufloxacin tosylate hydrate (A-61827 tosylate hydrate) 是一个氟喹诺酮类抗菌剂。
T1276	Danofloxacin mesylate 甲磺酸达氟沙星,CP 76136-27	DNA/RNA Synthesis; Antibacterial; Antibiotic	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
	Danofloxacin mesylate (CP 76136-27) 是一种兽医用氟喹诺酮类抗菌素。
T16542	Piromidic acid 吡咯酸,吡乙酸三氮萘	Antibacterial; Antibiotic	Microbiology/Virology
	Piromidic acid 是一种抗菌剂。它对革兰氏阴性菌和葡萄球菌具有活性，可研究肠道，泌尿和胆道感染。
T8048	Diphenylamine Hydrochloride	Others	Others
	Diphenylamine hydrochloride 分离自 coriander ，具有抗氧化作用。在农业中，它可用作杀菌剂及抗菌剂；在工业中，它可用作抗氧化剂及染料媒染剂。
T3867	Alpinetin 山姜素,(-)-alpinetin	BCL; PPAR	Apoptosis; DNA Damage/DNA Repair; Metabolism
	Alpinetin ((-)-alpinetin) 是从草豆蔻中分离得到的一种黄酮类天然产物，能够活化PPAR-γ，具有抗炎、抗菌活性。它通过抑制增殖、调节 Bcl-2 家族和 XIAP 表达、释放细胞色素 c 和激活 caspase 具有很强的抗肝癌和胰腺癌细胞作用。
T11392	Germacrene D	Antibacterial	Microbiology/Virology
	Germacrene D has antibacterial and antifungal activities and can be used as an adjuvant agent in the application of aminoglycosides and azoles. Germacrene D is isolated from Bursera species.
T74200	Glicophenone
	Glicophenone 作为一种抗细菌(antibacterial)剂，对MRSA OM481、MRSA OM505、MRSA OM584、MRSA OM623 以及MSSA 209P的MIC值均为32 μg/mL。
T73207	Laburnetin
	Laburnetin 是一种异黄酮类抗菌剂 (antibacterial agent)。Laburnetin 对真菌、S. vesicarium 具有抗菌活性。Laburnetin 增强了耐甲氧西林 (Methicillin) 金黄色葡萄球菌 (MRSA) 菌株对甲氧西林的敏感性。Laburnetin 可用于控制栽培物种的虫害。
TN5119	Taxoquinone	Tyrosinase; Antifection	Microbiology/Virology; Proteases/Proteasome
	Taxoquinone has strong antibacterial effect, it could be used as a promising antibacterial agent in food industry to inhibit the growth of certain important foodborne pathogens. It (100 ug/disc) displays potential anticandidal effect against Candia albica
T8261	Ceftazidime Pentahydrate 头孢他啶五水合物,头孢他啶	Antibacterial; Antibiotic	Microbiology/Virology
	Ceftazidime pentahydrate 是一种β-内酰胺类抗菌剂，对革兰氏阳性和革兰氏阴性需氧细菌有广谱活性，可静脉内或肌肉给药。它对肠杆菌科特别有效，对大多数 β-内酰胺酶具有抗水解作用。
TN1526	Corydalmine	P450; Antifection	Metabolism; Microbiology/Virology
	Corydalmine exhibits antibacterial activities against Staphylococcus aureus and methicillin-resistant S. aureus strains.1-Corydalmine significantly inhibits spore germination of all the fungi at 100 to 1500 ppm. l-Corydalmine also exhibits potent analgesic activity in preclinical models, it is under development as an oral analgesic agent.
T2S1797	Santalol 檀香醇；白檀油萜醇;檀香脑,檀香醇	Antioxidant; Antifungal	Microbiology/Virology; oxidation-reduction
	Santalol 是一种檀香醇的 α 和 β-异构体混合物。其中α-santalol 分离自檀香油中，是一种有前途的抗癌药，能够预防口腔癌、前列腺癌、乳腺癌和皮肤癌。
TN5288	Ergosterol peroxide glucoside 过氧化麦角甾醇葡萄糖苷,Ergosterol peroxide 3-O-β-D-glucopyranoside
	Ergosterol peroxide exhibits anti-cancer, amoebicidal, anticomplementary, antibacterial, antiviral, anti-oxdiant, and anti-melanogenic activities. Ergosterol peroxide could as an anti-atherosclerosis agent, it exhibits hACAT-1 and Lp-PLA2 inhibitory effec
TN1938	Mogroside VI 罗汉果甜苷 VI,罗汉果甜苷VI	Antifection	Microbiology/Virology
	Lo Han Kuo extract is a high intensive sweetening agent with desirable health benefits, such as prevention of dental caries through specific antibacterial properties, no-calorie levels related to obesity, and a low glycemic index to help manage blood suga
T14121	Actinonin (-)-Actinonin	Aminopeptidase	Metabolism
	Actinonin ((-)-Actinonin) is a naturally occurring antibacterial agent produced by Actinomyces and a potent reversible peptide deformylase (PDF) inhibitor with a Ki of 0.28 nM, it also is an apoptosis inducer. Actinonin inhibits aminopeptidase M, aminopeptidase N and leucine aminopeptidase, it also inhibits MMP-1, MMP-3, MMP-8, MMP-9, and hmeprin α with Ki values of 300 nM, 1,700 nM, 190 nM, 330 nM, and 20 nM, respectively. Actinonin has antiproliferative and antitumor activities[1][2][3][4][5].
T78490	Polygalacturonic acid Galacturonic acid polymer
	Polygalacturonic acid（Galacturonic acid polymer）为透明胶状物，构成细胞壁关键组分。该酸应用于制备银纳米颗粒（AgNPs），充当抗氧化剂与抗炎剂，防护细胞遭受ROS增高引起的损伤，并促进伤口愈合。Polygalacturonic acid纳米颗粒亦显示抗菌性能。
TN4592	Murrangatin	IL Receptor; TNF; COX; Prostaglandin Receptor	Apoptosis; GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Murrangatin may be a valuable anti-tumor-promoting agent, it can significantly inhibit Epstein-Barr virus early antigen (EBV-EA) activation, and preserve the high viability of Raji cells, it also exhibits cytotoxicity against cholangiocarcinoma cell line,

天然产物

Cat.No: T20446

Target: Endogenous Metabolite

Cat.No: T13355

Target: Antibacterial

Cat.No: T1314

Synonym: Irgasan,三氯生,Cloxifenolum

Target: NADPH, Antibacterial, Antibiotic, Autophagy, Antifungal

Protocatechualdehyde

Cat.No: T3018

Synonym: Protocatechuic aldehyde,3,4-Dihydroxybenzaldehyde,Rancinamycin IV,Catechaldehyde,原儿茶醛

Target: Reactive Oxygen Species, Antibacterial

(-)-TERPINEN-4-OL

Cat.No: TN6746

Target: Antibacterial

Tosufloxacin tosylate hydrate

Cat.No: T8046

Synonym: Tosufloxacin p-Toluenesulfonate Hydrate,A-61827 tosylate hydrate,对甲苯磺酸妥舒沙星水合物,T-3262 Tosylate Hydrate

Target: Others, Antibacterial, Antibiotic

Danofloxacin mesylate

Cat.No: T1276

Synonym: 甲磺酸达氟沙星,CP 76136-27

Target: DNA/RNA Synthesis, Antibacterial, Antibiotic

Cat.No: T16542

Synonym: 吡咯酸,吡乙酸三氮萘

Target: Antibacterial, Antibiotic

Diphenylamine Hydrochloride

Cat.No: T8048

Target: Others

Cat.No: T3867

Synonym: 山姜素,(-)-alpinetin

Target: BCL, PPAR

Cat.No: T11392

Target: Antibacterial

Cat.No: T74200

Cat.No: T73207

Cat.No: TN5119

Target: Tyrosinase, Antifection

Ceftazidime Pentahydrate

Cat.No: T8261

Synonym: 头孢他啶五水合物,头孢他啶

Target: Antibacterial, Antibiotic

Cat.No: TN1526

Target: P450, Antifection

Cat.No: T2S1797

Synonym: 檀香醇；白檀油萜醇;檀香脑,檀香醇

Target: Antioxidant, Antifungal

Ergosterol peroxide glucoside

Cat.No: TN5288

Synonym: 过氧化麦角甾醇葡萄糖苷,Ergosterol peroxide 3-O-β-D-glucopyranoside

Cat.No: TN1938

Synonym: 罗汉果甜苷 VI,罗汉果甜苷VI

Target: Antifection

Cat.No: T14121

Synonym: (-)-Actinonin

Target: Aminopeptidase

Polygalacturonic acid

Cat.No: T78490

Synonym: Galacturonic acid polymer

Cat.No: TN4592

Target: IL Receptor, TNF, COX, Prostaglandin Receptor

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